1.Definition: action that makes a problem or a disease (or its symptoms) worse

"The aggravation of her condition resulted from lack of care"

Related Noun(s):exacerbation

Category: General

2.Definition: an exasperated feeling of annoyance

Related Noun(s):exasperation

Category: Feelings

3.Definition: unfriendly behavior that causes anger or resentment

Related Noun(s):irritation, provocation

Category: General